The Independent Pharmacy

How Long Does Tadalafil Last After Taking It?

Andy Boysan
Andy Boysan
BPharm GPhC 2047716
Director & Superintendent Pharmacist

Understanding how long Tadalafil lasts is essential for effective treatment planning. Tadalafil’s duration, which is known for being longer than many other similar medications, plays an important role in deciding the best dosing and timing for individual needs. This flexibility allows patients and healthcare providers to tailor erectile dysfunction (ED) treatment plans to suit specific lifestyle factors and health conditions.

Key Takeaways

1 | One tablet can last up to 36 hours

2 | Effects start within 30 minutes to two hours

3 | Daily tablets provide continuous effectiveness

I’d like help to get an erection

There are different dosing options available: a lower daily dose provides continuous coverage, while higher doses are designed for as-needed use. Each approach has unique timing considerations that impact how and when tadalafil is most effective. This ED treatment guide explores what you need to know about how long tadalafil lasts.

When Does Tadalafil Start Working?

The onset time of Tadalafil depends on the dosage and how it’s prescribed. For as-needed doses, typically 10mg or 20mg, the medication begins working within 30 minutes to two hours after taking the pill. This fast-acting option is ideal for those who prefer flexibility and can plan around sexual activity. However, the effectiveness also depends on factors such as whether the medication is taken with or without food, as a heavy meal might affect how quickly your body absorbs it and how fast it works.

For people on a daily dose regimen (usually 2.5mg or 5mg) the onset is more gradual. It may take several days of consistent use before reaching its full effect. This option means that you have the potential to reach an erection at any time, without pre-planning for sex. Regardless of the dosing method, sexual stimulation is necessary for tadalafil to work effectively. Always follow your healthcare provider’s guidance for the best results.

Couple kissing in bed

How Long Does Tadalafil Last?

The duration of action for Tadalafil ED tablets varies depending on the dose and how it’s taken. For as-needed doses (10mg or 20mg), tadalafil remains active for up to 36 hours This extended window allows for greater flexibility, meaning you don’t have to precisely time sexual activity. Instead, you can enjoy a more natural and spontaneous sexual experience during this period, as the medication will help you to achieve an erection when you become aroused.

In contrast, the daily dose (2.5mg or 5mg) provides continuous coverage. This means tadalafil remains consistently active in the system, making it possible to achieve an erection at any time without needing to plan ahead. This approach is particularly beneficial for you if you prefer a more spontaneous lifestyle or engage in frequent sexual activity.

Both dosing options offer unique advantages, allowing you to choose what works best for your routine and personal preferences.

What Affects How Long Tadalafil Works?

Several factors can influence how long Tadalafil works, affecting both its duration and effectiveness.

  • Age plays a role, as older individuals may metabolise the medication more slowly, potentially prolonging its effects.
  • Health conditions, such as liver or kidney impairment, can also impact how the body processes tadalafil, making its effects last longer or requiring dose adjustments.3
  • Your diet is more likely to affect how quickly the medication works than how long it’s effective for. While Tadalafil can be taken with or without food, a heavy or high-fat meal may delay how quickly it starts working.
  • Alcohol consumption can also reduce effectiveness, as excessive alcohol may impair your ability to achieve an erection, even with the medication.
  • Other medications - such as nitrates, blood pressure drugs, or certain antibiotics - can interact with tadalafil, altering its effectiveness and safety

To maximise benefits and minimise risks, it’s important to follow your healthcare provider’s advice and consider how lifestyle factors may influence your medication’s performance.

Tadalafil Tablets (10mg & 20mg)
Tadalafil Tablets (10mg & 20mg)
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Timing Your Dose For Best Results

Timing your dose of Tadalafil correctly is key to achieving the best results. For as-needed doses (10mg or 20mg), it’s recommended to take the tablet 30 minutes to 2 hours before engaging in sexual activity. This allows the medication enough time to take effect. Tadalafil can be taken with or without food but consuming it with a heavy or high-fat meal may mean it takes a little longer to work.

For daily doses (2.5mg or 5mg), timing is less critical since the medication is designed to remain in your body so you can get an erection whenever is appropriate. To maintain consistent levels in the body, take the daily tablet at the same time each day. And it doesn’t matter whether that’s with or without food.

Whether using the on-demand or daily option, you should remember that sexual stimulation is required for Tadalafil to work. Following the recommended timing helps give you the best chance at getting an erection when you need one and maximises your chance of a satisfactory sexual encounter.

Understanding The '36-Hour' Window

The '36-hour' window often associated with Tadalafil refers to its extended duration of effectiveness, and not a continuous erection. After taking an as-needed dose (10mg or 20mg), Tadalafil remains active in the body for up to 36 hours, meaning you should achieve an erection during this time if sexually aroused. This provides freedom for a more spontaneous sexual encounter. Nevertheless, it’s important to remember that you’ll still need time for your erection to recover following ejaculation, just as you would if you had sex without using Tadalafil - so don’t expect to be able to perform again right away!

Tadalafil doesn’t cause an automatic or prolonged erection. Instead, it works by enhancing blood flow to the penis when stimulated, making it easier to achieve and maintain an erection naturally This flexibility is ideal for those who don’t necessarily know exactly when they are going to have sex.

The 36-hour window gives you the freedom to relax and enjoy intimacy without the pressure of precise timing, making it a popular ED treatment for people wanting a more natural and stress-free experience.

It is essential that you speak to a licensed medical professional before starting any ED medication. They can provide personalised, expert guidance, assess potential risks and ensure that your chosen treatment is safe and suitable for your health needs.

Remember:

Timing plays a crucial role in maximising Tadalafil’s effects, whether using it for as-needed or daily dosing.

Understanding how long Tadalafil lasts and its onset can help you fit the medication around your lifestyle and needs.

Factors like dosage, health conditions, and timing around meals also influence its effectiveness, making it important to consider these when planning your treatment.

For personalised advice and to determine the best option for you, consult one of our knowledgeable clinicians. Professional guidance ensures safe use and the best results, helping you make the most of Tadalafil’s benefits.

Start your journey today with a quick and discreet ED consultation - it takes only a minute. Get personalised recommendations tailored to your needs.

I’d like help to get an erection

Sources

  1. https://www.nhs.uk/medicines/tadalafil/common-questions-about-tadalafil/
  2. https://www.nhs.uk/medicines/tadalafil/how-and-when-to-take-tadalafil/
  3. https://doi.org/10.3389/fpubh.2022.1092353.
  4. https://bnf.nice.org.uk/interactions/tadalafil/

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Andy Boysan

Authored by

Andy Boysan
Andy Boysan
BPharm
2047716
Director & Superintendent Pharmacist

Andy is a co-founder and the Superintendent Pharmacist and Director at The Independent Pharmacy.

Daniel Hurley

Reviewed by

Daniel Hurley
Daniel Hurley
MPharm IP
2078790
Pharmacist Independent Prescriber

Dan is an experienced pharmacist having spent time working in both primary and secondary care. He currently supports our clinical team by providing robust clinical governance review of our internal processes and information.