Vydura 75mg Tablets

Migraine relief with Vydura

Vydura is a medicine that’s used to treat and prevent migraines. It contains the active ingredient rimegepant.

Vydura comes in an easy-to-take wafer form (oral lyophilisate), where it dissolves on or underneath your tongue. It’s the ideal migraine medication as not only is it easy to take but it gets to work quickly as you do not need to wait for a tablet to disperse in the stomach.

How effective is rimegepant (Vydura)?

Vydura has proven to be very effective in clinical trials. When being used for migraine relief, rimegepant is was found to:

• Give 59% of patients pain relief within two hours of taking
• Leave 21% of patients pain free within two hours
• Remove 35% of patients of their ‘most bothersome symptom’ within two hours
• Provided 42% of patients with continued pain relief between two and 48 hours after the first dose
• Meant that 86% of patients did not need any other pain relief in the first 24 hours

How does Vydura work to treat migraines?

Rimegepant belongs to a brand new class of migraine medications called ‘Gepants’. It blocks the receptors on neurons in the brain that calcitonin gene-related peptide (CGRP) binds to.

CGRP is involved in the symptoms and pain of migraines. Rimegepant can reduce the symptoms of migraine when you can feel it coming on and can also be taken preventatively to reduce the chance of migraines from happening.

Other prescription medications available

We stock a wide range of migraine relief medication, including other triptans, nasal sprays, and wafer melts.

Other triptans we stock:

Tablets

• Almotriptan 12.5mg tablets
• Migard (frovatriptan) 2.5mg tablets

Nasal Sprays

• Imigran (sumatriptan) 10mg & 20mg

Wafer Melts

• Maxalt Melt (rizatriptan) 10mg
• Rizatriptan 10 mg

Alternate (over-the-counter) medication for migraines

There are some over-the-counter medications that can be used initially to try and combat migraine pain and nausea. Some of the products include:

• Paracetamol
• Ibuprofen
• Aspirin
• Buccastem M to help with nausea.

Sources

• https://www.medicines.org.uk/e...

• https://migrainetrust.org/live...

• https://www.nice.org.uk/guidance/indevelopment/gid-ta10839

Vydura directions

You place one wafer below the tongue and let it dissolve. You don’t need to take it with food or drink. If you need, you can take another Vydura after 24 hours have passed since the first dose.

If you’re taking Vydura as a preventative treatment, you can take one wafer every other day to prevent the onset of migraine symptoms.

You should never take more than one Vydura wafer within 24 hours.

Vydura ingredients

Each Vydura tablet contains rimegepant sulfate, equivalent to 75 mg rimegepant.

Each tablet also contains: Gelatin, mannitol (E421), mint flavour, sucralose

Vydura side effects

Like all medications, you might experience side effects when taking Vydura (rimegepant).

Thankfully Vydura is extremely well tolerated the only common side effect is nausea.

Like all medications unexpected allergic reactions can happen. Leading to rash or shortness of breath. You should call 999 immediately if this happens.

You can read a full list of possible side effects in the patient information leaflet.

Vydura warnings

Vydura may be unsuitable for certain people. Do not take this product if you are allergic to rimegepant or any of the other listed ingredients.

Do not take this product if you have severe liver problems, or if you have reduced kidney function.

The following medicines should be avoided while taking Vydura:

• Itraconazole and clarithromycin (medicines used to treat fungal or bacterial infections)
• Ritonavir and efavirenz (medicines to treat HIV infections)
• Bosentan (a medicine used to treat high blood pressure)
• St. John’s wort (a herbal remedy used to treat depression)
• Phenobarbital (a medicine used to treat epilepsy)
• Rifampicin (a medicine used to treat tuberculosis)
• Modafinil (a medicine used to treat narcolepsy)
• Fluconazole and erythromycin (medicines used to treat fungal or bacterial infections)
• Diltiazem, quinidine, and verapamil (medicines used to treat an abnormal heart rhythm, chest pain (angina) or high blood pressure)
• Cyclosporin (a medicine used to prevent organ rejection after an organ transplant)

If you need help regarding medications please speak to one of our helpful medical team and we can assist you