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Mounjaro has rapidly become a popular treatment for people looking to shed excess weight, but did you know it may work differently for men and women? Research suggests that while both sexes can see positive results, they could also vary depending on whether you’re biologically male or female. Understanding how Mounjaro affects each group can help you to set realistic expectations about your potential weight loss and make the best decisions for your health.
There’s been plenty of news stories about women finding successful weight loss after taking Mounjaro, but far less has been reported about its use in obese and overweight men. The good news is that research has found that it works for men too, although exact results can vary depending on factors such as metabolism, body composition and even hormonal differences. This means that the amount of weight that can be lost using Mounjaro may vary between different sexes.
By understanding how Mounjaro may work for you and what you can expect to experience while taking it, you’ll feel more confident about starting, or continuing, your weight loss journey.
1 | Men may experience different weight loss results compared to women on Mounjaro
2 | Hormonal and metabolic differences influence how men respond to the treatment
3 | Men typically experience fewer side effects than women
Absolutely, there’s no doubt Mounjaro can help men lose weight. Recent studies show men taking Mounjaro can lose up to 18.1% of their body weight, making it a highly effective weight loss option. So, how does it work?
Mounjaro is part of a class of medicines known as GLP-1 agonists. It works by copying your body’s hormones that control hunger and blood sugar levels, making you feel fuller for longer and less likely to crave food or overeat. This means managing hunger better, eating less and enjoying higher energy levels – all essential for sustainable weight loss.
So far so good, and this is the same for both sexes. But here’s the twist – hormonal differences between men and women can influence how the treatment works. Women typically tend to have higher levels of body fat, and it’s distributed in a different way to men. Some scientists say this may affect the way Mounjaro works. In the same studies that saw men lose up to 18.1% of baseline body weight, women lost up to 24.6%. However,show that it's possible to lose a significant amount of weight using Mounjaro.
Take a look at our Mounjaro Guides to learn more about weight loss injections, how they work and their benefits.
Men using Mounjaro can achieve remarkable weight loss. According to results from the SURMOUNT-1 clinical trial, men lost up to 18.1% of their body weight over 72 weeks. By comparison, in the same study women lost slightly more but the difference was modest. Overall participants lost up to 22.5% or 24kg with 89% of those taking tirzepatide losing at least 5% of their body weight compared to just 28% of those on a placebo medication. A placebo medication is a fake treatment that looks just like a real treatment, but has no medical effect.
While men did lose slightly less than women, the results are still significant. Factors like how much weight you have to lose to start with, your muscle mass and your metabolism can all affect how much weight you lose. Diet, physical activity and consistent use of the medication will also impact your weight loss too. Alongside a solid routine that includes a healthy diet and regular exercise, Mounjaro is still a powerful weight loss tool for men and can help you reach your health goals.
Men taking Mounjaro and other weight loss treatments often experience fewer and less severe side effects than women, particularly nausea and vomiting. Scientists aren’t entirely sure why men and women react differently and say more research is needed but suggest it may be due to metabolic and physiological differences. Men’s faster metabolism and higher muscle mass may affect how fast Mounjaro is processed, reducing some of the side effects.
That said, men can’t avoid them entirely. Common side effects like mild nausea, fatigue and digestive changes can still occur as the body adjusts to the medication. Men may also experience injection site reactions, such as redness and swelling, though these are usually mild and temporary.
The important thing is to monitor how you’re feeling and talk to your doctor if anything feels off, especially if side effects are persistent or severe. With patience and the right approach, most side effects are mild, manageable and short-lived.
There’s no reason why men can’t consider Mounjaro and other weight loss injections to help them reach their health goals, but setting realistic expectations is important – weight loss takes time and success often depends on pairing treatment with a healthier lifestyle. Commitment is another important piece of the puzzle. Staying consistent with medication and making long-term changes are essential if you’re going to keep the weight off long-term.
You may also face other social pressures, especially when eating out or drinking, which can make it tougher to stick to your goals. Hopefully you can get the support of your family and friends at times when making healthy choices is more challenging, so that you can remain as consistent as possible.
It is essential that you speak to a licensed medical professional before starting any weight loss medication. They can provide personalised, expert guidance, assess potential risks and ensure that your chosen treatment is safe and suitable for your health needs.
There’s nothing to say that men can’t lose significant amounts of weight on Mounjaro. In fact, research suggests the opposite. While your weight loss journey may look a little different to that of a woman, Mounjaro is still a highly effective option. Try not to compare yourself to others, be realistic about what you want to achieve and pair Mounjaro with healthy habits like regular exercising and balanced eating for sustainable weight loss. Remember, this isn’t about quick fixes, it’s about creating a healthier, happier and more confident version of yourself.
If you want to know more about whether Mounjaro or other weight loss injections are the right choice for you why not book one of our weight loss consultations? A free, discreet consultation takes just a few minutes to complete. Our healthcare professionals will talk to you about your health goals before making recommendations for the best treatment.
Sources
https://www.marbellahospital.com/news-Mounjaro-Treatment-for-Weight-Loss-in-Marbella
https://pubmed.ncbi.nlm.nih.gov/35658024/
https://www.sciencedirect.com/science/article/pii/S073510972407445X?via%3Dihub
https://pmc.ncbi.nlm.nih.gov/articles/PMC8950819/
https://www.forbes.com/sites/ariannajohnson/2024/09/11/women-taking-mounjaro-and-zepbound-lose-more-weight-than-men-new-study-suggests-what-to-know/
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